Dihydropyridine calcium channel antagonists as antidepressant drugs in mice and rats

Behavioral despair in mice: a primary screening test for antidepressants.

Porsolt Rd, Aurélie Bertin, M Jalfre · PubMed · 1977 · 3.3K citations

Depressed State, Psychopharmacology, Mental Health +19

Antidepressants: Neurochemical, Behavioral and Clinical Perspectives

P. Jenner · Journal of Neurology Neurosurgery & Psychiatry · 1982 · 164 citations · Full text

Clinical Perspectives, Psychiatry, Psychotropic Medication +11

Functional evidence for subsensitivity of noradrenergic α2 receptors after chronic desipramine treatment

Christina Spyraki, H.C. Fibiger · Life Sciences · 1980 · 150 citations

Noradrenergic α2 Receptors, Psychiatry, Functional Selectivity +12

Chemistry and pharmacology of compounds related to 4-(4-hydroxy-4-phenyl-piperidino)-butyrophenone

Paul A. J. Janssen, Anton H. M. Jageneau, K H Schellekens · Psychopharmacology · 1960 · 141 citations

Medicinal Chemistry, Heterocyclic, Biochemistry +5

BIOASSAY OF RAUWOLFIA ROOTS AND ALKALOIDS

Bernard Rubin, Marvin H. Malone, Margaret H. Waugh et al. · Journal of Pharmacology and Experimental Therapeutics · 1957 · 132 citations

Botany, Herbal Medicine, Phytopharmacology +2