Concepedia

Ophiobolin M and analogues, noncompetitive inhibitors of ivermectin binding with nematocidal activity

Athanasios Tsipouras, A. Adefarati, Jan S. Tkacz, Easter G. Frazier, Susan P. Rohrer, Elizabeth T. Birzin, Avery Rosegay, Deborah L. Zink, Michael Goetz, Sheo B. Singh,

Bioorganic & Medicinal Chemistry · 1996 · 53 citations · 14 references

Concepts

MedicineMedicinal ChemistryPharmacologyDrug DesignDrug DiscoveryMolecular PharmacologyAntiparasitic AgentsAntiparasitic PharmacologyAntiparasitic PharmacotherapyDrug-receptor InteractionsEnzyme InhibitionLigand BindingAntiparasitic PharmacodynamicsNematocidal ActivityNoncompetitive InhibitionPharmacodynamics Of Antiparasitic AgentsPharmacodynamics Of Antiparasitic Drugs

References

14

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

Mark A. Bradford · Analytical Biochemistry · 1976 · 225.4K citations

Life Sciences, Biochemistry, Protein Biochemistry +7

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Marion M. Bradford · Analytical Biochemistry · 1976 · 211.2K citations

Life Sciences, Biochemistry, Protein Biochemistry +7

THE GENETICS OF <i>CAENORHABDITIS ELEGANS</i>

Sydney Brenner · Genetics · 1974 · 15.5K citations · Full text

Life Sciences, Biology, Genetics +14

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans

Doris Cully, Demetrios K. Vassilatis, Ken K. Liu et al. · Nature · 1994 · 757 citations

Life Sciences, Molecular Biology, Neuroscience +12