Diabetic KKAy mice exhibit increased hepatic PPARγ1 gene expression and develop hepatic steatosis upon chronic treatment with antidiabetic thiazolidinediones

An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

Jürgen M. Lehmann, Linda B. Moore, Tracey Smith-Oliver et al. · Journal of Biological Chemistry · 1995 · 3.6K citations · Full text

PPARγ Is Required for the Differentiation of Adipose Tissue In Vivo and In Vitro

Evan D. Rosen, Pasha Sarraf, Amy E. Troy et al. · Molecular Cell · 1999 · 2K citations · Full text

Metabolic Syndrome, Developmental Biology, Lipid Synthesis +10

PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene.

Kristina Schoonjans, Julia Peinado‐Onsurbe, Anne‐Marie Lefebvre et al. · The EMBO Journal · 1996 · 1.2K citations · Full text

Transcriptional Regulation, Lipoprotein Lipase Gene, Biochemistry +7

Terminal Differentiation of Human Breast Cancer through PPARγ

Elisabetta Mueller, Pasha Sarraf, Peter Tontonoz et al. · Molecular Cell · 1998 · 841 citations · Full text

Tumor Biology, Terminal Differentiation, Breast Oncology +5

Tissue Distribution and Quantification of the Expression of mRNAs of Peroxisome Proliferator–Activated Receptors and Liver X Receptor-α in Humans: No Alteration in Adipose Tissue of Obese and NIDDM Patients

Didier Auboeuf, Jennifer Rieusset, Lluís Fajas et al. · Diabetes · 1997 · 691 citations