Concepedia

Atorvastatin inhibits proliferation and apoptosis, but induces senescence in hepatic myofibroblasts and thereby attenuates hepatic fibrosis in rats

Sabine Klein, J Klösel, Robert Schierwagen, Christian Körner, M Granzow, Sebastian Huss, Irela Gretchen Reza Mazar, Susanne N. Weber, Peter F. M. van der Ven, Ursula Pieper‐Fürst,

Laboratory Investigation · 2012 · 100 citations · 23 references

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References

23

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.4K citations · Full text

, , +15

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

Zhenbang Chen, Lloyd C. Trotman, David R. Shaffer et al. · Nature · 2005 · 2K citations · Full text

, , +16

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

Florence Debacq‐Chainiaux, Jorge D. Erusalimsky, Judith Campisi et al. · Nature Protocols · 2009 · 1.6K citations · Full text

, , +11

Liver fibrosis

Ramón Bataller · Journal of Clinical Investigation · 2005 · 1.5K citations · Full text

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Senescence‐associated β‐galactosidase is lysosomal β‐galactosidase

Bo Yun Lee, Jung A Han, Jun Sub Im et al. · Aging Cell · 2006 · 1.4K citations · Full text

, , +16