Concepedia

Enhanced potency of perfluorinated thalidomide derivatives for inhibition of LPS-induced tumor necrosis factor-α production is associated with a change of mechanism of action

Satomi Niwayama, Christine Loh, Benjamin E. Turk, Jun O. Liu, Hiroyuki Miyachi, Yuichi Hashimoto

Bioorganic & Medicinal Chemistry Letters · 1998 · 19 citations · 16 references

DOI

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References

16

Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes.

E P Sampaio, Euzenir Nunes Sarno, Ruth Galilly et al. · The Journal of Experimental Medicine · 1991 · 1.2K citations · Full text

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Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation.

André L. Moreira, E P Sampaio, A Zmuidzinas et al. · The Journal of Experimental Medicine · 1993 · 1.1K citations · Full text

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Organofluorine compounds in medicinal chemistry and biomedical applications

International Journal of Biochemistry · 1994 · 489 citations

, , +5

Asymmetric synthesis of R-β-amino butanoic acid and S-β-tyrosine: Homochiral lithium amide equivalents for Michael additions to α,β-unsaturated esters.

Stephen G. Davies, Osamu Ichihara · Tetrahedron Asymmetry · 1991 · 256 citations

, , +9

Structural Modifications of Thalidomide Produce Analogs with Enhanced Tumor Necrosis Factor Inhibitory Activity

George W. Muller, Laura G. Corral, Mary G. Shire et al. · Journal of Medicinal Chemistry · 1996 · 157 citations · Full text

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