Concepedia

Role of immune dysfunction in pathogenesis of type 1 diabetes mellitus in children

Jinshui He, Pu-Song Xie, Daoshu Luo, Chengjun Sun, Yugui Zhang, Fuxing Liu

Asian Pacific Journal of Tropical Medicine · 2014 · 28 citations · 13 references

DOIFull text

Open access

Abstract

Immune dysfunction, with upregulation of inflammatory factors such as IL-1α, IL-6, TNF-α and MIP-1α, downregulation of IL-10 and Tregs, plays an important role in the pathogenesis of T1DM in children.

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