Effect of allopurinol and oxipurinol on pyrimidine synthesis in cultured human fibroblasts

Human Hypoxanthine Phosphoribosyltransferase

Thomas A. Krenitsky, R Papaioannou, Gertrude B. Elion · Journal of Biological Chemistry · 1969 · 237 citations · Full text

Human Hypoxanthine Phosphoribosyltransferase, Biosynthesis, Cellular Enzymology +12

Effect of allopurinol (4-Hydroxypyrazolo-(3,4-d)pyrimidine) on serum and urinary uric acid in primary and secondary gout

Ts’ai-Fan Yű, Alexander B. Gutman · The American Journal of Medicine · 1964 · 231 citations

Urology, Urinary Uric Acid, Medicine +4

The Effectiveness of the Xanthine Oxidase Inhibitor Allopurinol in the Treatment of Gout

James R. Klinenberg · Annals of Internal Medicine · 1965 · 216 citations

Rheumatology, Uric Acid Production, Urology +14

Orotidylic Acid Decarboxylase: Inhibition Studies with Azauridine 5′-Phosphate

Robert E. Handschumacher · Journal of Biological Chemistry · 1960 · 185 citations · Full text

Bioorganic Chemistry, Natural Sciences, Orotidylic Acid Decarboxylase +3

Pseudofeedback Inhibition of Purine Synthesis by 6-Mercaptopurine Ribonucleotide and Other Purine Analogues

Robert J. McCollister, Walter R. Gilbert, Doris M. Ashton et al. · Journal of Biological Chemistry · 1964 · 165 citations · Full text

Purine Synthesis, Biochemistry, Medicine +4