Orotidylic Acid Decarboxylase: Inhibition Studies with Azauridine 5′-Phosphate

ENZYMATIC SYNTHESIS OF PYRIMIDINE NUCLEOTIDES. OROTIDINE-5'-PHOSPHATE AND URIDINE-5'-PHOSPHATE

Irving Lieberman, Arthur Kornberg, Ernest S. Simms · Journal of Biological Chemistry · 1955 · 337 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

The Biochemical Activity of 6-Azauridine: Interference with Pyrimidine Metabolism in Transplantable Mouse Tumors

C. A. Pasternak, Robert E. Handschumacher · Journal of Biological Chemistry · 1959 · 137 citations · Full text

Medicine, Oncology, Pharmacology +14

Inhibition of orotidylic acid decarboxylase, a primary site of carcinostasis by 6-azauracil

Robert E. Handschumacher, C. A. Pasternak · Biochimica et Biophysica Acta · 1958 · 122 citations

Medicine, Oncology, Pharmacology +4

Studies on the carcinostatic activity in mice of 6-azauracil riboside (azauridine), in comparison with that of 6-azauracil.

Julian J. Jaffe, Robert E. Handschumacher, Arnold D. Welch · PubMed · 1957 · 60 citations

Medicine, Oncology, Pharmacology +9

Microbial studies of 6-azauracil, an antagonist of uracil.

Robert E. Handschumacher, Arnold D. Welch · PubMed · 1956 · 52 citations

Life Sciences, Microbiology, Antimicrobial Pharmacology +13