Utilization of side-chain precursors for penicillin biosynthesis in a high-producing strain of Penicillium chrysogenum

Synthesis of Penicillin: 6-Aminopenicillanic Acid in Penicillin Fermentations

F. R. Batchelor, F. P. Doyle, J. H. C. Nayler et al. · Nature · 1959 · 388 citations

Medicinal Chemistry, Antibiotics, Penicillin Fermentations +5

Localization of the pathway of the penicillin biosynthesis in Penicillium chrysogenum.

Wally H. Müller, Theo P. van der Krift, A. J. Krouwer et al. · The EMBO Journal · 1991 · 167 citations · Full text

Biology, Industrial Mycology, Penicillium Chrysogenum +5

Involvement of microbodies in penicillin biosynthesis

Wally H. Müller, Roelof A.L. Bovenberg, Marloes H. Groothuis et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 1992 · 116 citations

Biosynthesis, Engineering, Biotransformation +5

Purification to homogeneity and characterization of acyl coenzyme A:6-aminopenicillanic acid acyltransferase of Penicillium chrysogenum

Emilio Fernández Álvarez, Jesús M. Cantoral, José Luis Barredo et al. · Antimicrobial Agents and Chemotherapy · 1987 · 113 citations · Full text

Penicillium Chrysogenum, Biosynthesis, Engineering +13

Subcellular compartmentation of penicillin biosynthesis in Penicillium chrysogenum. The amino acid precursors are derived from the vacuole.

Thomas Lendenfeld, D. Ghali, Markus Wolschek et al. · Journal of Biological Chemistry · 1993 · 79 citations · Full text

Engineering, Penicillin Biosynthesis, Cellular Localization +18