Concepedia

Methoxycarbonyl-etomidate

Joseph F. Cotten, S. Shaukat Husain, Stuart A. Forman, Keith Miller, Elizabeth Kelly, Hieu Nguyen, Douglas E. Raines

Anesthesiology · 2009 · 128 citations · 41 references

DOIFull text

Open access

Abstract

MOC-etomidate is an etomidate analogue that retains etomidate's important favorable pharmacological properties. However, it is rapidly metabolized, ultra-short-acting, and does not produce prolonged adrenocortical suppression after bolus administration.

References

41

Hydrocortisone Therapy for Patients with Septic Shock

Charles L. Sprung, Djillali Annane, Didier Keh et al. · New England Journal of Medicine · 2008 · 2.1K citations · Full text

The Pharmacokinetics of the New Short-acting Opioid Remifentanil (GI87084B) in Healthy Adult Male Volunteers

Talmage D. Egan, Harry J. M. Lemmens, Pierre Fiset et al. · Anesthesiology · 1993 · 627 citations · Full text

General anesthetic actions <i>in vivo</i> strongly attenuated by a point mutation in the GABA <sub>A</sub> receptor β3 subunit

Rachel Jurd, Margarete Arrasa, Sachar Lambert et al. · The FASEB Journal · 2002 · 559 citations

Inhibition of Adrenal Steroidogenesis by the Anesthetic Etomidate

R. Lee Wagner, Paul F. White, Patricia B. Kan et al. · New England Journal of Medicine · 1984 · 546 citations

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Sympathetic Responses to Induction of Anesthesia in Humans with Propofol or Etomidate

Thomas J. Ebert, Michael Muzi, Richard J. Berens et al. · Anesthesiology · 1992 · 475 citations · Full text

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