PHYTOCHEMICAL INVESTIGATION OF<i>Wissadula periplocifolia</i>(L.) C. Presl AND EVALUATION OF ITS ANTIBACTERIAL ACTIVITY

Yanna Carolina Ferreira Teles, Roosevelt Albuquerque Gomes, Micaelly da Silva Oliveira, Kaio L. de Lucena, José Soares do Nascimento, Maria de Fátima Agra, John O. Igoli, Alexander I. Gray, María de Fátima Vanderlei de Souza

Química Nova · 2014 · 14 citations · 1 references

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Abstract

A phytochemical study on the aerial parts of Wissadula periplocifolia using chromatographic techniques has led to the isolation of sitosterol (1a), stigmasterol (1b), sitosterol 3-O-β-D-glucopyranoside (2a), stigmasterol 3-O-β-D-glucopyranoside (2b), phaeophytin A (3), 13²-hydroxy-(13²-S)-phaeophytin A (4), phaeophytin B (5), 17³-ethoxyphaeophorbide (6), 3,4-seco-urs-4(23),20(30)-dien-3-oic acid (7), 3-oxo-21β-H-hop-22(29)-ene (8), dammaradienone (9a), and taraxastenone (9b). The isolated compounds were characterised by spectroscopic analysis. A preliminary assay to evaluate the antibacterial activity of W. periplocifolia extracts and fractions showed that the dichloromethane, ethyl acetate, and n-butanol fractions were active against Enterococcus faecalis.

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