Concepedia

Protodecarboxylation of benzoic acids under radical conditions

Sangwon Seo, John B. Taylor, Michael F. Greaney

Chemical Communications · 2012 · 107 citations · 26 references

DOI

Concepts

Abstract

A new approach to protodecarboxylation is described that enhances the substrate scope for benzoic acids. The reaction uses oxidative radical conditions to decarboxylate a variety of acids in acetonitrile.

References

26

Palladium- and Copper-Catalyzed Arylation of Carbon−Hydrogen Bonds

Olafs Daugulis, Hien‐Quang Do, Dmitry Shabashov · Accounts of Chemical Research · 2009 · 2K citations · Full text

, , +16

Carboxylates as sources of carbon nucleophiles and electrophiles: comparison of decarboxylative and decarbonylative pathways

Wojciech I. Dzik, Paul P. Lange, Lukas J. Gooßen · Chemical Science · 2012 · 509 citations

, , +15

Carboxylic Acids as Traceless Directing Groups for Formal <i>meta</i>‐Selective Direct Arylation

Josep Cornellà, Marika Righi, Igor Larrosa · Angewandte Chemie International Edition · 2011 · 310 citations

, , +10

Silver(I)-catalyzed oxidative decarboxylation of acids by peroxydisulfate. Role of silver(II)

James M. Anderson, Jay K. Kochi · Journal of the American Chemical Society · 1970 · 296 citations

, , +6

Decarboxylative CH Cross‐Coupling of Azoles

Fengzhi Zhang, Michael F. Greaney · Angewandte Chemie International Edition · 2010 · 257 citations

, , +8