Concepedia

MALDI-TOF Mass Spectrometry Detection of Pathogens in Vectors: The Borrelia crocidurae/Ornithodoros sonrai Paradigm

Aurélien Fotso Fotso, Oleg Mediannikov, Georges Diatta, Lionel Alméras, Christophe Flaudrops, Philippe Parola, Michel Drancourt

PLoS neglected tropical diseases · 2014 · 62 citations · 20 references

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Abstract

After the development of an appropriate database, MALDI-TOF-MS can be used to identify tick species and the presence of relapsing fever borreliae in a single assay. This work paves the way for the use of MALDI-TOF-MS for the dual identification of vectors and vectorized pathogens.

References

20

Ongoing Revolution in Bacteriology: Routine Identification of Bacteria by Matrix‐Assisted Laser Desorption Ionization Time‐of‐Flight Mass Spectrometry

Piseth Seng, Michel Drancourt, Frédérique Gouriet et al. · Clinical Infectious Diseases · 2009 · 1.8K citations

A bacterial genome in flux: the twelve linear and nine circular extrachromosomal DNAs in an infectious isolate of the Lyme disease spirochete <i>Borrelia burgdorferi</i>

Sherwood Casjens, N. Palmer, R van Vugt et al. · Molecular Microbiology · 2000 · 844 citations

Population Genetics of Ixodes scapularis (Acari: Ixodidae) Based on Mitochondrial 16S and 12S Genes

Douglas E. Norris, J. S. H. Klompen, James E. Keirans et al. · Journal of Medical Entomology · 1996 · 290 citations

Bacterial species identification from MALDI-TOF mass spectra through data analysis and machine learning

Katrien De Bruyne, Bram Slabbinck, Willem Waegeman et al. · Systematic and Applied Microbiology · 2011 · 220 citations

, , +7

Incidence of tick-borne relapsing fever in west Africa: longitudinal study

Laurence Vial, Georges Diatta, Adama Tall et al. · The Lancet · 2006 · 180 citations

, , +4