Identification of Penicillin and other Beta-Lactam Resistance in Streptococcus Pneumoniae by Polymerase Chain Reaction

Horizontal transfer of penicillin-binding protein genes in penicillin-resistant clinical isolates of Streptococcus pneumoniae.

Christopher G. Dowson, A. Hutchison, J.A. Brannigan et al. · Proceedings of the National Academy of Sciences · 1989 · 401 citations · Full text

Klebsiella Pneumoniae, Bacteriology, Molecular Biology +20

Interspecies recombinational events during the evolution of altered PBP 2x genes in penicillin‐resistant clinical isolates of <i>Streptococcus pneumoniae</i>

Götz Laible, Brian G. Spratt, Regine Hakenbeck · Molecular Microbiology · 1991 · 280 citations

Microbial Pathogens, Klebsiella Pneumoniae, Molecular Biology +22

Penicillin-binding proteins 2b and 2x of Streptococcus pneumoniae are primary resistance determinants for different classes of beta-lactam antibiotics

T Grebe, Regine Hakenbeck · Antimicrobial Agents and Chemotherapy · 1996 · 242 citations · Full text

Streptococcus Pneumoniae, Antimicrobial Susceptibility, Point Mutations +14

Multiple changes of penicillin-binding proteins in penicillin-resistant clinical isolates of Streptococcus pneumoniae

Regine Hakenbeck, Martha Tarpay, Alexander Tomasz · Antimicrobial Agents and Chemotherapy · 1980 · 222 citations · Full text

Streptococcus Pneumoniae, Antimicrobial Susceptibility, Health Sciences +15

Genetics of resistance to third‐generation cephalosporins in clinical isolates of <i>Streptococcus pneumoniae</i>

Rosario Múñoz, Christopher G. Dowson, M. Daniels et al. · Molecular Microbiology · 1992 · 194 citations