Prospects for the future in the management of carcinoma of the breast: The biological fall out from clinical trials

Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and design

Richard Peto, Malcolm C. Pike, P. Armitage et al. · British Journal of Cancer · 1976 · 2.3K citations · Full text

Public Health, Biostatistics, Clinical Medicine +12

The Importance of Beta, the Type II Error and Sample Size in the Design and Interpretation of the Randomized Control Trial

Jennie A. Freiman, Thomas C. Chalmers, Harry Smith et al. · New England Journal of Medicine · 1978 · 1.6K citations

Public Health, Biostatistics, Experimental Design +16

Dose-Response Effect of Adjuvant Chemotherapy in Breast Cancer

Gianni Bonadonna, Pinuccia Valagussa · New England Journal of Medicine · 1981 · 777 citations

Medicine, Oncology, Breast Oncology +11

The contribution of recent nsabp clinical trials of primary breast cancer therapy to an understanding of tumor biology—an overview of findings

Bernard Fisher, Carol Redmond, Edwin R. Fisher · Cancer · 1980 · 240 citations · Full text

Medicine, Cancer Biology, Oncology +13

Low incidence of estrogen receptor in breast carcinomas with rapid rates of cellular replication

John S. Meyer, B. Ramanath Rao, Sue C. Stevens et al. · Cancer · 1977 · 193 citations

Medicine, Endocrinology, Oncology +13