Assessment of a multiple-dose drug interaction between ezetimibe, a novel selective cholesterol absorption inhibitor and gemfibrozil

Larisa Reyderman, Teddy Kosoglou, Paul Statkevich, L.J.C. Pember, Tanya Boutros, Stephen E. Maxwell, M B Affrime, Vishal Batra

International Journal of Clinical Pharmacology and Therapeutics · 2004 · 37 citations · 0 references

Abstract

The coadministration of ezetimibe and gemfibrozil in patients is unlikely to cause a clinically significant drug interaction. The coadministration of these agents is a promising approach for patients with mixed dyslipidemia. Additional clinical studies are warranted.