Human Cathelicidin LL-37 Is a Chemoattractant for Eosinophils and Neutrophils That Acts via Formyl-Peptide Receptors

G. Sandra Tjabringa, Dennis K. Ninaber, Jan W. Drijfhout, Klaus F. Rabe, Pieter S. Hiemstra

International Archives of Allergy and Immunology · 2006 · 245 citations · 51 references

Abstract

LL-37 displays chemotactic activity for eosinophils and neutrophils, and this activity is mediated via an FPR. These results suggest that LL-37 may play a role in inflammatory lung diseases such as asthma and COPD.

References

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