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Antagonism of L-type Ca2+ channels CaV1.3 and CaV1.2 by 1,4-dihydropyrimidines and 4H-pyrans as dihydropyridine mimics

Soosung Kang, Garry Cooper, Sara F. Dunne, Chi‐Hao Luan, D. James Surmeier, Richard B. Silverman

Bioorganic & Medicinal Chemistry · 2013 · 43 citations · 18 references

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18

‘Rejuvenation’ protects neurons in mouse models of Parkinson’s disease

C. Savio Chan, Jaime N. Guzmán, Ema Ilijić et al. · Nature · 2007 · 906 citations

, , +16

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1

Jaime N. Guzmán, Javier Sánchez-Padilla, David L. Wokosin et al. · Nature · 2010 · 843 citations

, , +14

Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state.

Bruce P. Bean · Proceedings of the National Academy of Sciences · 1984 · 833 citations · Full text

, , +17

Dihydropyrimidine calcium channel blockers. 3. 3-Carbamoyl-4-aryl-1,2,3,4-tetrahydro-6-methyl-5-pyrimidinecarboxylic acid esters as orally effective antihypertensive agents

Karnail S. Atwal, Brian N. Swanson, Steven E. Unger et al. · Journal of Medicinal Chemistry · 1991 · 784 citations

, , +12

Lanthanide Triflate Catalyzed Biginelli Reaction. One-Pot Synthesis of Dihydropyrimidinones under Solvent-Free Conditions

Yun Ma, Changtao Qian, Limin Wang et al. · The Journal of Organic Chemistry · 2000 · 518 citations

, , +5