Evidence that random and imprinted Xist expression is controlled by preemptive methylation

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Gene Action in the X-chromosome of the Mouse (Mus musculus L.)

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Knockout Mouse, Developmental Biology, Cytogenetics +8

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

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Developmental Biology, Embryonic Lethality, Epigenetic Change +8

A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome

Carolyn J. Brown, Andrea Ballabio, James L. Rupert et al. · Nature · 1991 · 1.5K citations

Chromatin, Developmental Biology, Genetic Disorder +9

The human XIST gene: Analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus

Carolyn J. Brown, Brian Hendrich, Jim L. Rupert et al. · Cell · 1992 · 1.3K citations

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