Role of the poly(ADP-ribose)polymerase activity in vancomycin-induced renal injury

Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis.

Scott H. Kaufmann, Serge Desnoyers, Yvonne Ottaviano et al. · PubMed · 1993 · 1.9K citations

Life Sciences, Biochemistry, Molecular Biology +14

Resistance to endotoxic shock as a consequence of defective NF‐κB activation in poly (ADP‐ribose) polymerase‐1 deficient mice

F. Javier Oliver · The EMBO Journal · 1999 · 576 citations · Full text

Life Sciences, Immunology, Molecular Biology +11

Oxidant injury of cells. DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide.

Ingrid U. Schraufstätter, Daniel B. Hinshaw, Paul A. Hyslop et al. · Journal of Clinical Investigation · 1986 · 513 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Characterization of the necrotic cleavage of poly(ADP-ribose) polymerase (PARP-1): implication of lysosomal proteases

Stéphane Gobeil, Claudia Boucher, D. Nadeau et al. · Cell Death and Differentiation · 2001 · 338 citations

Life Sciences, Molecular Biology, Pathology +14

In vitro and in vivo evidence suggesting a role for iron in cisplatin-induced nephrotoxicity

Radhakrishna Baliga, Zhiwei Zhang, Mithra Baliga et al. · Kidney International · 1998 · 303 citations · Full text

Medicine, Nephrology, Toxicology +14