Glucose-induced insulin secretion is potentiated by a new imidazoline compound

Phentolamine block of K _ATP channels is mediated by Kir6.2

Peter Proks, Frances M. Ashcroft · Proceedings of the National Academy of Sciences · 1997 · 149 citations

Medicine, Cell Biology, Molecular Biology +17

An insulin-releasing property of imidazoline derivatives is not limited to compounds that block ?-adrenoceptors

Axel Schulz, A. Hasselblatt · Naunyn-Schmiedeberg s Archives of Pharmacology · 1989 · 116 citations

Medicine, Endocrinology, Pharmacology +6

Design and Synthesis of Imidazoline Derivatives Active on Glucose Homeostasis in a Rat Model of Type II Diabetes. 1. Synthesis and Biological Activities of <i>N</i>-Benzyl-<i>N</i> ‘-(arylalkyl)-2-(4‘,5‘-dihydro-1‘<i>H</i>-imidazol-2‘-yl)piperazines

Frédéric Rondu, Gae͏̈lle Le Bihan, Xuan Wang et al. · Journal of Medicinal Chemistry · 1997 · 107 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

The α2-adrenoceptor antagonist efaroxan modulates K+ATP channels in insulin-secreting cells

Susan L.F. Chan, Mark J. Dunne, Michael R. Stillings et al. · European Journal of Pharmacology · 1991 · 103 citations

Life Sciences, Endocrinology, Pharmacology +13

Imidazoline Compounds Stimulate Insulin Release by Inhibition of KATP Channels and Interaction With the Exocytotic Machinery

Alexander M. Efanov, Ioulia B Efanova, Olof Larsson et al. · Diabetes · 1996 · 94 citations

Life Sciences, Cell Biology, Pharmacology +17