Synthesis and characterisation of polyamine–poly(ethylene glycol) constructs for DNA binding and gene delivery

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

Philip L. Felgner, Thomas R. Gadek, Mai Marie Holm et al. · Proceedings of the National Academy of Sciences · 1987 · 5K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +15

Direct Gene Transfer into Mouse Muscle in Vivo

Jon A. Wolff, Robert W. Malone, Phillip Williams et al. · Science · 1990 · 4.2K citations

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A novel cationic liposome reagent for efficient transfection of mammalian cells

Xiang Gao, Leaf Huang · Biochemical and Biophysical Research Communications · 1991 · 845 citations

Pharmacy, Biotechnology, Pharmaceutics +16

The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes

MX Tang, FC Szoka · Gene Therapy · 1997 · 804 citations

Natural Sciences, Biochemistry, Chemistry +15

Activation of the Complement System by Synthetic DNA Complexes: A Potential Barrier for Intravenous Gene Delivery

Christian Plank, Karl Mechtler, Francis C. Szoka et al. · Human Gene Therapy · 1996 · 583 citations

Pharmacy, Immunology, Molecular Pharmaceutics +17