Concepedia

Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors

Alessandro F. Moretto, Steve Kirincich, W. Xu, Michael J. Smith, Z. Wan, Douglas Wilson, Bruce Follows, Eva Binnun, Diane Joseph‐McCarthy, Kenneth W. Foreman,

Bioorganic & Medicinal Chemistry · 2005 · 79 citations · 32 references

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References

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Increased Energy Expenditure, Decreased Adiposity, and Tissue-Specific Insulin Sensitivity in Protein-Tyrosine Phosphatase 1B-Deficient Mice

Lori D. Klaman, Olivier Boss, Odile D. Peroni et al. · Molecular and Cellular Biology · 2000 · 1.2K citations

, , +17

QXP: Powerful, rapid computer algorithms for structure-based drug design

Colin McMartin, Regine S. Bohacek · Journal of Computer-Aided Molecular Design · 1997 · 512 citations

, , +12

Regulation of PTP1B via Glutathionylation of the Active Site Cysteine 215

W C Barrett, Jon P. DeGnore, Simone König et al. · Biochemistry · 1999 · 492 citations

, , +17

PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice

Bradley A. Zinker, Cristina M. Rondinone, James M. Trevillyan et al. · Proceedings of the National Academy of Sciences · 2002 · 416 citations

, , +17

Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: A paradigm for inhibitor design

Yoram A. Puius, Yu Zhao, Michael Sullivan et al. · Proceedings of the National Academy of Sciences · 1997 · 402 citations

, , +17