Reduced podocyte expression of α3β1 integrins and podocyte depletion in patients with primary focal segmental glomerulosclerosis and chronic PAN-treated rats

WT-1 is required for early kidney development

Jordan A. Kreidberg, Hannu Sariola, Janet M. Loring et al. · Cell · 1993 · 2K citations

Medicine, Nephrology, Organogenesis +6

NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome

Nicolas Boute, Olivier Gribouval, Séverine Roselli et al. · Nature Genetics · 2000 · 1.4K citations

Medicine, Genetics, Nephrology +13

Mutations in ACTN4, encoding α-actinin-4, cause familial focal segmental glomerulosclerosis

Joshua M. Kaplan, Sung Hyun Kim, Kathryn N. North et al. · Nature Genetics · 2000 · 1.2K citations

Medicine, Genetics, Molecular Genetics +12

A Mutation in the <i>TRPC6</i> Cation Channel Causes Familial Focal Segmental Glomerulosclerosis

Michelle P. Winn, Peter J. Conlon, Kelvin L. Lynn et al. · Science · 2005 · 1.1K citations

Medicine, Molecular Genetics, Nephrology +17

TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function

Jochen Reiser, Krishna R. Polu, Clemens Möller et al. · Nature Genetics · 2005 · 858 citations · Full text

Life Sciences, Nephrology, Physiology +12