O 6 -Benzylguanine-mediated enhancement of nitrosourea activity in Mer − central nervous system tumor xenografts - implications for clinical trials

Mammalian O6-alkylguanine-DNA alkyltransferase: regulation and importance in response to alkylating carcinogenic and therapeutic agents.

Anthony E. Pegg · PubMed · 1990 · 738 citations

Oncogenic Agent, Medicine, Mammalian O6-alkylguanine-dna Alkyltransferase +7

O6-benzylguanine and its role in chemotherapy.

M. Eileen Dolan, Anthony E. Pegg · PubMed · 1997 · 216 citations

Tumor Biology, Medicinal Chemistry, Oncogenic Agent +11

Purification and properties of O6-methylguanine-DNA transmethylase from rat liver.

Anthony E. Pegg, Laurie Wiest, Robert S. Foote et al. · Journal of Biological Chemistry · 1983 · 183 citations · Full text

Biochemistry, Natural Sciences, Oligonucleotide +4

Experimental chemotherapy of human medulloblastoma cell lines and transplantable xenografts with bifunctional alkylating agents.

Henry S. Friedman, O. Michael Colvin, Stephen X. Skapek et al. · PubMed · 1988 · 132 citations

Pharmacotherapy, Tumor Biology, Neuro-oncology +18

Correlation between O⁶-methylguanine-DNA-methyltransferase activity and resistance of human cells to the cytotoxic and mutagenic effect of N-methyl-N′-nitro-N-nitrosoguanidine

Jeanne Y. Domoradzki, Anthony E. Pegg, M. Eileen Dolan et al. · Carcinogenesis · 1984 · 118 citations