ChemBioChem · 2011 · 23 citations · 23 references
Life SciencesBiochemistryChemistryDrug DesignDrug DiscoveryStructural BiologyCombinatorial Peptide SynthesisMacromolecular AssemblyProtein StructureStructural ElucidationGlycopeptide SynthesisX-ray Crystallographic Refinement
Small changes for better X-rays: The synthesis of all 20 natural amino acid-derived selenazole units now makes it possible to create diverse selenium-labeled peptides as X-ray crystallographic tools with which to map the polyspecific binding sites of P-glycoprotein. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
Stephen G. Aller, Jodie Yu, Andrew B. Ward et al. · Science · 2009 · 1.9K citations · Full text
Medicine, Biochemistry, Pharmacology +12
Communication between Multiple Drug Binding Sites on P-glycoprotein
Catherine Martin, G. Berridge, Christopher F. Higgins et al. · Molecular Pharmacology · 2000 · 415 citations