Qinghai Zhang

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

Stephen G. Aller, Jodie Yu, Andrew B. Ward et al. · Science · 2009 · 1.9K citations · Full text

Medicine, Biochemistry, Pharmacology +12

Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate α-synuclein fibrilization

Daryl A. Bosco, Douglas M. Fowler, Qinghai Zhang et al. · Nature Chemical Biology · 2006 · 348 citations

Life Sciences, Neurology, Neuroscience +17

Structure of a cation-bound multidrug and toxic compound extrusion transporter

Xiao He, Paul Szewczyk, Andrey Karyakin et al. · Nature · 2010 · 274 citations · Full text

Medicine, Pharmaceutics, Pharmacology +10

Metabolite-initiated protein misfolding may trigger Alzheimer's disease

Qinghai Zhang, Evan T. Powers, Jorgé Nieva et al. · Proceedings of the National Academy of Sciences · 2004 · 197 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein

Paul Szewczyk, Houchao Tao, Aaron P. McGrath et al. · Acta Crystallographica Section D Biological Crystallography · 2015 · 181 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17