Knockdown of PgP resensitizes leukemic cells to proteasome inhibitors

A Phase 2 Study of Bortezomib in Relapsed, Refractory Myeloma

Paul G. Richardson, Bart Barlogie, James R. Berenson et al. · New England Journal of Medicine · 2003 · 2.6K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +10

Bortezomib or High-Dose Dexamethasone for Relapsed Multiple Myeloma

Paul G. Richardson, Pieter Sonneveld, Michael W. Schuster et al. · New England Journal of Medicine · 2005 · 2.5K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +14

Cell Surface P-Glycoprotein Associated with Multidrug Resistance in Mammalian Cell Lines

Norbert Kartner, John R. Riordan, Victor Ling · Science · 1983 · 1K citations

Medicine, Oncology, Pharmacology +15

Multicenter Phase II Study of Bortezomib in Patients With Relapsed or Refractory Mantle Cell Lymphoma

Richard I. Fisher, Steven H. Bernstein, Brad S. Kahl et al. · Journal of Clinical Oncology · 2006 · 708 citations

Medicine, Hematology, Oncology +15

Drug-resistance in multiple myeloma and non-Hodgkin's lymphoma: detection of P-glycoprotein and potential circumvention by addition of verapamil to chemotherapy.

William S. Dalton, Thomas M. Grogan, Paul S. Meltzer et al. · Journal of Clinical Oncology · 1989 · 560 citations

Medicine, Oncology, Pharmacology +15