Archives of Dermatology · 1963 · 38 citations · 7 references
Natural SciencesBiophysicsDermatologyBiophotonicsRadiation BiophysicsRadiation DosimetryDrug-induced PhotosensitivityPhotochemical KineticsPhotochemistrySpectral SensitivityUltraviolet Radiation BiologyConcentrationCutaneous Phototoxic ReactionsDrug PhotosensitizationLight DosimetryPhotosensitive MaterialsPhotosensitivity MechanismsPhotosensitizersPhotosensitizing Compounds
Both tetracycline (TET) and demethylchlortetracycline (DMC) are photosensitive substances under the conditions of this experiment. Ultraviolet wavelengths which pass through common window glass (>315 mμ) will activate this response in human skin. DMC appears to have greater photoresponse potential per unit concentration than tetracycline. A hot quartz lamp appears to be an inadequate light source for these studies, when compared with natural sunlight.
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