Use of Cre-adenovirus and CAR transgenic mice for efficient deletion of genes in post-thymic T cells

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice.

Jacques J. Peschon, Philip Morrissey, Kenneth H. Grabstein et al. · The Journal of Experimental Medicine · 1994 · 1.6K citations · Full text

Life Sciences, Genetics, Immunology +17

Deletion of a DNA Polymerase β Gene Segment in T Cells Using Cell Type-Specific Gene Targeting

Hua Gu, Jamey D. Marth, Paul C. Orban et al. · Science · 1994 · 1.4K citations

Life Sciences, Genetics, Molecular Genetics +17

Cre recombinase: The universal reagent for genome tailoring

András Nagy · genesis · 2000 · 1.2K citations

Life Sciences, Genetics, Molecular Biology +16

Expression of Cre recombinase in the developing mouse limb bud driven by a <i>Prxl</i> enhancer

Malcolm Logan, James F. Martin, András Nagy et al. · genesis · 2002 · 1K citations

Life Sciences, Developmental Biology, Genetics +17

Disruption of overlapping transcripts in the ROSA βgeo 26 gene trap strain leads to widespread expression of β-galactosidase in mouse embryos and hematopoietic cells

Brian Zambrowicz, Akira Imamoto, Steve Fiering et al. · Proceedings of the National Academy of Sciences · 1997 · 871 citations

Life Sciences, Genetics, Molecular Genetics +17