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Targeting the ANG2/TIE2 Axis Inhibits Tumor Growth and Metastasis by Impairing Angiogenesis and Disabling Rebounds of Proangiogenic Myeloid Cells

Roberta Mazzieri, Ferdinando Pucci, Davide Moi, Erika Zonari, Anna Ranghetti, Alvise Berti, Letterio S. Politi, Bernhard Gentner, Jeffrey L. Brown, Luigi Naldini,

Cancer Cell · 2011 · 627 citations · 37 references

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37

Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis

Chitra Suri, Pamela F. Jones, Sybill Patan et al. · Cell · 1996 · 2.9K citations · Full text

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Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

Marta Pàez‐Ribes, Elizabeth Allen, James Hudock et al. · Cancer Cell · 2009 · 2.3K citations · Full text

, , +16

Vessel Cooption, Regression, and Growth in Tumors Mediated by Angiopoietins and VEGF

Jocelyn Holash, Peter C. Maisonpierre, Debra Compton et al. · Science · 1999 · 2.2K citations

, , +17

Tie2/Angiopoietin-1 Signaling Regulates Hematopoietic Stem Cell Quiescence in the Bone Marrow Niche

Fumio Arai, Atsushi Hirao, Masako Ohmura et al. · Cell · 2004 · 1.9K citations · Full text

, , +11

Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis

John M.L. Ebos, Christina R. Lee, William Cruz‐Muñoz et al. · Cancer Cell · 2009 · 1.7K citations · Full text

, , +16