Endoglin haploinsufficiency reduces radiation-induced fibrosis and telangiectasia formation in mouse kidneys

Direct binding of Smad3 and Smad4 to critical TGFβ‐inducible elements in the promoter of human plasminogen activator inhibitor‐type 1 gene

Sylviane Dennler · The EMBO Journal · 1998 · 1.8K citations · Full text

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Endoglin, a TGF-β binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1

Kimberly A. McAllister, K.M. Grogg, David W. Johnson et al. · Nature Genetics · 1994 · 1.5K citations · Full text

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Mutations in the activin receptor–like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2

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Balancing the activation state of the endothelium via two distinct TGF‐β type I receptors

Marie‐José Goumans · The EMBO Journal · 2002 · 1.1K citations · Full text

Life Sciences, Immunology, Molecular Biology +12

Activin receptor-like kinase 1 modulates transforming growth factor-β1 signaling in the regulation of angiogenesis

S. Paul Oh, Tsugio Seki, Kendrick A. Goss et al. · Proceedings of the National Academy of Sciences · 2000 · 861 citations

Life Sciences, Developmental Biology, Genetics +17