Ellipticine and derivatives induce breakage of L1210 cells DNA in vitro

Bioactivation as a Model for Drug Design Bioreductive Alkylation

Harold W. Moore · Science · 1977 · 433 citations

Medicine, Pharmacology, Drug Design +5

A New Antitumoral Agent: 9-Hydroxyellipticine. Possibility of a Rational Design of Anticancerous Drugs in the Series of DNA Intercalating Drugs

Jean‐Bernard Le Pecq, Nguyen‐Dat‐Xuong, Charles Gosse et al. · Proceedings of the National Academy of Sciences · 1974 · 231 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Synthesis of the tumour-inhibitory alkaloids, ellipticine, 9-methoxyellipticine, and related pyrido[4,3-b]carbazoles

LK Dalton, S Demerac, BC Elmes et al. · Australian Journal of Chemistry · 1967 · 211 citations

Pharmacy, Chemistry, Medicinal Chemistry +7

Association of mammalian cell death with a specific endonucleolytic degradation of DNA

Jerry R. Williams, John B. Little, William U. Shipley · Nature · 1974 · 169 citations

Life Sciences, Cell Biology, Molecular Biology +13

Effect of mitomycin C on mammalian cells in culture

Aaron J. Shatkin, E. Reich, Richard M. Franklin et al. · Biochimica et Biophysica Acta · 1962 · 117 citations

Life Sciences, Biochemistry, Cell Biology +13