Synthesis and biological activity of novel inhibitors of topoisomerase I: 2-Aryl-substituted 2-bis-1H-benzimidazoles

DNA topology and its biological effects

Choice Reviews Online · 1991 · 609 citations

Life Sciences, Genetics, Molecular Biology +14

Eukaryotic DNA topoisomerases: two forms of type I DNA topoisomerases from HeLa cell nuclei.

Leroy F. Liu, Kathryn G. Miller · Proceedings of the National Academy of Sciences · 1981 · 349 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +8

The molecular structure of the complex of Hoechst 33258 and the DNA dodecamer d(CGCGAATTCGCG)

Maikun Teng, Nassim Usman, Christin Frederick et al. · Nucleic Acids Research · 1988 · 333 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +14

DNA minor groove-binding ligands: a different class of mammalian DNA topoisomerase I inhibitors.

A Y Chen, C. Yu, Barbara Gatto et al. · Proceedings of the National Academy of Sciences · 1993 · 273 citations

Medicine, Pharmacology, Cancer Pharmacology +12

Use of the tetrazolium assay in measuring the response of human tumor cells to ionizing radiation.

P. Price, Trevor J. McMillan · PubMed · 1990 · 246 citations

Medicine, Oncology, Radiation Oncology +17