A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis - Concepedia

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A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis

77

Citations

41

References

2014

Year

Tobias Berg, Silvia Thoene, Damian Yap, Tracee Wee, Nathalie Schoeler, Patty Rosten, Emilia L. Lim, Misha Bilenky, Andrew J. Mungall, Thomas Oellerich,

Abstract

Key Points A functional demonstration of the oncogenic role of mutated EZH2 in a mouse model is presented. The global effects of mutated EZH2 on expression and epigenome have been characterized.

References

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