A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds

Stuart A. Lipton, Yun‐Beom Choi, Zhuo‐Hua Pan, +6

Nature

NeurophysiologyNitric OxideMedicineRedox-based MechanismReactive Nitrogen Specie +12

Interaction of Nitric Oxide Synthase with the Postsynaptic Density Protein PSD-95 and α1-Syntrophin Mediated by PDZ Domains

Jay E. Brenman, Daniel S. Chao, Stephen Gee, +9

Cell

Neurodegenerative DiseasesSignal TransductionMolecular PhysiologyBiochemistrySynaptic Signaling +12

Protein S-nitrosylation: a physiological signal for neuronal nitric oxide

Samie R. Jaffrey, Hediye Erdjument‐Bromage, Christopher D. Ferris, +2

Nature Cell Biology

Molecular NeuroscienceMolecular PhysiologyNeurophysiologyProtein S-nitrosylationReactive Nitrogen Specie +7

Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin.

Jonathan S. Stamler, O Jaraki, Jason W. Osborne, +6

Proceedings of the National Academy of Sciences

Nitric OxideRedox BiologyOxidative StressInflammationFree Nitric Oxide +16

S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding

Makoto R. Hara, Nishant Agrawal, Sangwon F. Kim, +11

Nature Cell Biology

Signal TransductionCell RegulationNatural SciencesApoptosisApoptotic Cell Death +10

<i>S</i> -Nitrosylation of Parkin Regulates Ubiquitination and Compromises Parkin's Protective Function

Kenny K. K. Chung, Bobby Thomas, Xiaojie Li, +5

Science

Molecular RegulationParkin Regulates UbiquitinationParkin SubstratesProtective FunctionDopamine Neurons +18

β-Arrestin-dependent, G Protein-independent ERK1/2 Activation by the β2 Adrenergic Receptor

Sudha K. Shenoy, Matthew T. Drake, Christopher Nelson, +7

Journal of Biological Chemistry

Cardiac Function in Mice Overexpressing the β-Adrenergic Receptor Kinase or a βARK Inhibitor

Walter J. Koch, Howard A. Rockman, Philippe Samama, +4

Science

Cardiac FunctionCardiac MuscleHeart FailureβArk InhibitorCardiovascular Pharmacology +17

Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: implications for nitric oxide signaling.

Guillermo García‐Cardeña, Philmo Oh, J Liu, +2

Proceedings of the National Academy of Sciences

Nitric OxideMembrane AssociationCellular PhysiologyOxidative StressInflammation +17

Nitric oxide activates TRP channels by cysteine S-nitrosylation

Takashi Yoshida, Ryuji Inoue, Takashi Morii, +7

Nature Chemical Biology

Molecular PhysiologySignal TransductionBiochemistryReactive Nitrogen SpecieNitric Oxide +5