Noninvasive fluorine-19 NMR study of fluoropyrimidine metabolism in cell cultures of human pancreatic and colon adenocarcinoma

Fluorinated Pyrimidines and Their Nucleosides

Charles Heidelberger · 1975 · 338 citations

Pharmacy, Chemistry, Medicinal Chemistry +12

Effect of excess folates and deoxyinosine on the activity and site of action of 5-fluorouracil.

Ronald M. Evans, Laskin Jd, Hakala Mt · PubMed · 1981 · 283 citations

Medicine, Biochemistry, Pharmacology +14

Cytotoxicity of 5-fluoro-2'-deoxyuridine: requirement for reduced folate cofactors and antagonism by methotrexate.

Buddy Ullman, M Lee, David W. Martin et al. · Proceedings of the National Academy of Sciences · 1978 · 195 citations · Full text

Medicine, Oncology, Pharmacology +14

Biochemical determinants of responsiveness to 5-fluorouracil and its derivatives in xenografts of human colorectal adenocarcinomas in mice.

Janet A. Houghton, Stephen J. Maroda, John O. Phillips et al. · PubMed · 1981 · 194 citations

Medicine, Biochemistry, Oncology +13

5-Flourouracil metabolism monitored in vivo by 19F NMR

A. N. Stevens, Peter G. Morris, R. A. Iles et al. · British Journal of Cancer · 1984 · 158 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +10