Hyperglucagonemia of Renal Failure

Abstract

A B S T R A C T Elevation of plasma glucagon concentra- tion has been observed in starvation and illnesses as- sociated with increased catabolism such as diabetes mel- litus and severe infections. Thus, we examined plasma glucose, immunoreactive insulin (IRI, microunits per milliliter) and glucagon (IRG, picograms per milli- liter) responses to a beef meal (1 g/kg body wt) and in- travenous glucose (1.5 g/min for 45 min) in patients with chronic renal failure (CRF).