A SEROLOGICAL INVESTIGATION OF SHEEP LEUCOCYTE ANTIGENS

Abstract

SUMMARY Forty‐eight leucocytotoxic antisera obtained from parous ewes and from the recipients of osteoarticular and skin allografts were tested with a panel of leucocytes from unrelated sheep. Computer analysis of the serological data and limited adsorption studies have enabled the tentative identification of twenty‐one sheep leucocyte antigens. By adsorption erythrocytes have been shown to lack these antigens. It is postulated that the antigens belong to one or possibly more system(s) for which the term ShL‐A is proposed.