Concepedia

Asymmetric Baylis–Hillman reactions: catalysis using a chiral pyrrolizidine base

Anthony G. M. Barrett, Andrew S. Cook, Akio Kamimura

Chemical Communications · 1998 · 128 citations · 8 references

DOI

Concepts

Abstract

A novel chiral pyrrolizidine base 5 derived from L-proline promotes the Baylis–Hillman reaction of ethyl and methyl vinyl ketones with electron deficient aromatic aldehydes with moderate levels of enantiomeric excess.

References

8

The Baylis-Hillman reaction: A novel carbon-carbon bond forming reaction

Deevi Basavaiah, Polisetti Dharma Rao, Rachakonda Suguna Hyma · Tetrahedron · 1996 · 858 citations

, , +2

Synthetic potential of the tertiary-amine-catalysed reaction of activated vinyl carbanions with aldehydes

Siegfried E. Drewes, Gregory Roos · Tetrahedron · 1988 · 677 citations

, , +3

The Asymmetric Baylis−Hillman Reaction

Linda Joy Brzezinski, Sara Rafel, James W. Leahy · Journal of the American Chemical Society · 1997 · 198 citations

, , +4

Catalytic enantioselective Baylis-Hillman reactions. Correlation between pressure and enantiomeric excess

István E. Markó, Paul R. Giles, Nigel J. Hindley · Tetrahedron · 1997 · 147 citations

, , +11

An Unexpected Rate AccelerationPractical Improvements in the Baylis−Hillman Reaction

Sara Rafel, James W. Leahy · The Journal of Organic Chemistry · 1997 · 117 citations

, , +4