Absence of MHC class II gene expression in a patient with a single amino acid substitution in the class II transactivator protein CIITA

Regulation of MHC Class II Expression by Interferon-γ Mediated by the Transactivator Gene CIITA

Viktor Steimle, Claire-Anne Siegrist, Annick Mühlethaler‐Mottet et al. · Science · 1994 · 899 citations

Life Sciences, Genetics, Immunology +16

Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

Viktor Steimle, L. Otten, Madeleine Zufferey et al. · Cell · 1993 · 840 citations

Life Sciences, Genetics, Molecular Genetics +13

Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex

Adrian P. Kelly, Stephen H. Powis, L A Kerr et al. · Nature · 1992 · 409 citations

Life Sciences, Genetics, Molecular Biology +9

Mice Lacking the MHC Class II Transactivator (CIITA) Show Tissue-Specific Impairment of MHC Class II Expression

Cheong‐Hee Chang, Sylvie Guerder, Soon–Cheol Hong et al. · Immunity · 1996 · 353 citations · Full text

Life Sciences, Genetics, Immunology +17

A novel DNA-binding regulatory factor is mutated in primary MHC class II deficiency (bare lymphocyte syndrome).

Viktor Steimle, Bénédicte Durand, Emmanuèle Barras et al. · Genes & Development · 1995 · 339 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15