Solitary Fibrous Tumors of the Pleura: Clinicopathological Characteristics, Immunohistochemical Profiles, and Surgical Outcomes with Long-Term Follow-Up

Abstract

Complete pleural resection with adequate safe margins can achieve satisfactory outcomes in a majority of cases, but long-term follow-up for all patients is recommended due to the potential for late tumor recurrence. Conventional clinicopathological variables do not affect prognosis. However, IHC studies of the CD-34 and bcl-2 biomarkers can be important for further differential diagnosis, and p16 expression can be used to predict tumor recurrence.