Publication | Closed Access
Organocatalytic Asymmetric Strecker Reaction of Di- and Trifluoromethyl Ketoimines. Remarkable Fluorine Effect
192
Citations
57
References
2011
Year
HalogenationChemical EngineeringNovel OrganocatalystsEngineeringFluorous SynthesisOrganic ChemistryTrifluoromethyl KetoiminesEnantioselective Strecker ReactionChemistryRemarkable Fluorine EffectEnantioselective SynthesisBiomolecular Engineering
A highly enantioselective Strecker reaction of difluoromethyl and trifluoromethyl ketoimines was developed. Remarkable fluorine effect on the reactivity and selectivity is observed and discussed.
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