The Journal of Clinical Endocrinology & Metabolism · 1968 · 19 citations · 0 references
MedicineEndocrinologyNephrologyEndocrine SurgeryMineral MetabolismRenal PathophysiologyDisorders Of Phosphate MetabolismParathyroid Hormone PhysiologyPhosphate HomeostasisRenal DiseaseRenal Function TestsRenal Mineral HandlingAdrenocortical SecretionPhosphate Balance DisordersPhosphate Homeostasis DisordersRenal Phosphate ExcretionRenal Phosphate ReabsorptionRenal Phosphate Transport
Renal excretion of phosphorus was studied in 52 acromegalic patients by means of the phosphate excretion index (PEI) described by Nordin and Fraser. Forty-eight patients were classified as having “active” acromegaly and 69% of these had PEI values below the lower limit of the range of a control series (39 subjects), whereas only 29% had plasma phosphorus values above the upper limit of the range of the controls. Postoperative PEI and plasma phosphorus values in patients classed as “inactive” after intrasellar implantation of 90Y, and who had normal adrenocortical function, were within normal limits. PEI also returned to normal in 7 patients classified as “improved.”