Autoimmune Pancreatocholangitis, Non-Autoimmune Pancreatitis and Primary Sclerosing Cholangitis: A Comparative Morphological and Immunological Analysis

Abstract

AIPC is mainly a disease of the pancreatic head with possible extension into the periphery of the gland and/or into the biliary tract/gallbladder. The morphology of AIPC, as well as the immune- and stromal reaction is characteristic and comparable between cases with and without biliary tract involvement. Immunological markers (IgG4, CXCR5, CXCL13) can be of diagnostic relevance in specific settings.