Nature · 2002 · 422 citations · 28 references
MedicineCancer BiologyOncologyCarcinogenesisMolecular OncologyNeoplasiaCancer Cell SignalingCancer ProgressionColorectal CancerMalignant NeoplasmsTumor Suppressor Gene InactivationTumor Suppressor GenesGastrointestinal Polyps
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Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a
Manuel Serrano, Athena W. Lin, Mila E. McCurrach et al. · Cell · 1997 · 5.1K citations · Full text
Medicine, Cell Biology, Oncology +10
Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
Gabriele Bergers, Rolf A. Brekken, Gerald McMahon et al. · Nature Cell Biology · 2000 · 2.8K citations · Full text
Medicine, Cancer Biology, Oncology +14
A serine/threonine kinase gene defective in Peutz–Jeghers syndrome
Akseli Hemminki, David Markie, Ian Tomlinson et al. · Nature · 1998 · 1.6K citations
Role of the INK4a Locus in Tumor Suppression and Cell Mortality
Manuel Serrano, Han‐Woong Lee, Lynda Chin et al. · Cell · 1996 · 1.6K citations · Full text
Tumor Suppression at the Mouse INK4a Locus Mediated by the Alternative Reading Frame Product p19
Takehiko Kamijo, Frédérique Zindy, Martine F. Roussel et al. · Cell · 1997 · 1.6K citations · Full text