Wnt/β-catenin signaling stimulates matrix catabolic genes and activity in articular chondrocytes: its possible role in joint degeneration

Osteoarthritis cartilage histopathology: grading and staging

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Medicine, Orthopaedic Surgery, Pathology +12

Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels

Paul D. Benya · Cell · 1982 · 2.3K citations

Life Sciences, Cell Biology, Developmental Biology +14

Biochemical and Metabolic Abnormalities in Articular Cartilage from Osteo-Arthritic Human Hips

Henry J. Mankin, HOWARD DORFMAN, Louis Lippiello et al. · Journal of Bone and Joint Surgery · 1971 · 2K citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +17

Wnt/β-Catenin/Tcf Signaling Induces the Transcription of Axin2, a Negative Regulator of the Signaling Pathway

Eek‐hoon Jho, Tong Zhang, Claire Domon–Dell et al. · Molecular and Cellular Biology · 2002 · 1.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

A new member of the frizzled family from Drosophila functions as a Wingless receptor

Purnima Bhanot, Marcel R.M. van den Brink, Cindy Harryman Samos et al. · Nature · 1996 · 1.5K citations

Life Sciences, Biology, Genetics +8