The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

Brenda J. Reinhart, Frank J. Slack, Michael Basson et al. · Nature · 2000 · 4.9K citations

Developmental Timing, Developmental Biology, Genetics +6

RAS Is Regulated by the let-7 MicroRNA Family

Steven Johnson, Jaclyn Shingara, Mike Byrom et al. · Cell · 2005 · 3.6K citations · Full text

Functional Genomics, Ras Is, Microrna Detection +5

Widespread changes in protein synthesis induced by microRNAs

Matthias Selbach, Björn Schwanhäußer, Nadine Thierfelder et al. · Nature · 2008 · 3.4K citations

Genetics, Microrna Detection, Small Rna +4

Argonaute2 Is the Catalytic Engine of Mammalian RNAi

Jidong Liu, Michelle A. Carmell, Fabiola V. Rivas et al. · Science · 2004 · 2.7K citations

Engineering, Genetics, Catalytic Engine +11

Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA

Amy E. Pasquinelli, Brenda J. Reinhart, Frank J. Slack et al. · Nature · 2000 · 2.5K citations

Developmental Biology, Genetics, Rna Biology +8