The Impact of Partial and Complete Loss-of-Function Mutations in Endothelial Lipase on High-Density Lipoprotein Levels and Functionality in Humans - Concepedia

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Publication | Open Access

The Impact of Partial and Complete Loss-of-Function Mutations in Endothelial Lipase on High-Density Lipoprotein Levels and Functionality in Humans

DOI Full Paper Access

61

Citations

39

References

2012

Year

Roshni R. Singaraja, Suthesh Sivapalaratnam, Kees Hovingh, Marie‐Pierre Dubé, José Castro‐Perez, Heidi L. Collins, Steven J. Adelman, Meliana Riwanto, Jasmin Manz, Brian K. Hubbard,

Circulation Cardiovascular Genetics

Abstract

Our data suggest that the impact of LIPG mutations is directly related to their effect on endothelial lipase function and support that antagonism of endothelial lipase function improves cardioprotection.

References

	Year	Citations

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