Permeability classification of representative fluoroquinolones by a cell culture method

A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability

Gordon L. Amidon, Hans Lennernäs, Vinod P. Shah et al. · Pharmaceutical Research · 1995 · 5.3K citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16

Active intestinal secretion of the fluoroquinolone antibacterials ciprofloxacin, norfloxacin and pefloxacin; a common secretory pathway?

Nina M. Griffiths, Barry H. Hirst, N. L. Simmons · Journal of Pharmacology and Experimental Therapeutics · 1994 · 90 citations

Life Sciences, Microbiology, Pharmacology +17

Fluoroquinolone (ciprofloxacin) secretion by human intestinal epithelial (Caco‐2) cells

Megan E. Cavet, Mike West, N. L. Simmons · British Journal of Pharmacology · 1997 · 67 citations · Full text

Medicine, Pharmacology, Cellular Pharmacology +14

Active secretion of the fluoroquinolone ciprofloxacin by human intestinal epithelial Caco‐2 cell layers

Nina M. Griffiths, Barry H. Hirst, Nicholas L. Simmons · British Journal of Pharmacology · 1993 · 64 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Secretory Mechanisms of Grepafloxacin and Levofloxacin in the Human Intestinal Cell Line Caco-2

Hiroaki Yamaguchi, Ikuko Yano, Yukiya Hashimoto et al. · Journal of Pharmacology and Experimental Therapeutics · 2000 · 60 citations

Medicine, Cell Biology, Pharmacology +14